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Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE(−/−) mice

Increasing evidence suggests thrombospondin-1 (TSP-1), a potent proatherogenic matricellular protein, as a putative link between hyperglycemia and atherosclerotic complications in diabetes. We previously reported that the micronutrient chromium picolinate (CrP), with long-standing cardiovascular ben...

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Detalles Bibliográficos
Autores principales: Ganguly, Rituparna, Sahu, Soumyadip, Ohanyan, Vahagn, Haney, Rebecca, Chavez, Ronaldo J., Shah, Shivani, Yalamanchili, Siri, Raman, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366888/
https://www.ncbi.nlm.nih.gov/pubmed/28345659
http://dx.doi.org/10.1038/srep45279