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Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges
Defensin peptides are essential for innate immunity in humans and other living systems, as they provide protection against infectious pathogens and regulate the immune response. Here, we report the solution structure of rattusin (RTSN), an α-defensin-related peptide, which revealed a novel C(2)-symm...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366907/ https://www.ncbi.nlm.nih.gov/pubmed/28345637 http://dx.doi.org/10.1038/srep45282 |