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Brain arousal regulation as response predictor for antidepressant therapy in major depression

A tonically high level of brain arousal and its hyperstable regulation is supposed to be a pathogenic factor in major depression. Preclinical studies indicate that most antidepressants may counteract this dysregulation. Therefore, it was hypothesized that responders to antidepressants show a) a high...

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Detalles Bibliográficos
Autores principales: Schmidt, Frank M., Sander, Christian, Dietz, Marie-Elisa, Nowak, Claudia, Schröder, Thomas, Mergl, Roland, Schönknecht, Peter, Himmerich, Hubertus, Hegerl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366924/
https://www.ncbi.nlm.nih.gov/pubmed/28345662
http://dx.doi.org/10.1038/srep45187