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Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity

The present study, we design and synthesize the novel dihydropyridine derivatives, i.e., 3 (a-e) and 5 (a-e) and evaluated, anticonvulsant activity. Initially due to the lacuna of LCC, we modeled the protein through modeller 9.15v and evaluated through servers. Docking studies were performed with th...

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Detalles Bibliográficos
Autores principales: Saddala, Madhu Sudhana, Kandimalla, Ramesh, Adi, Pradeepkiran Jangampalli, Bhashyam, Sainath Sri, Asupatri, Usha Rani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366925/
https://www.ncbi.nlm.nih.gov/pubmed/28345598
http://dx.doi.org/10.1038/srep45211