Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na(+) and K(+): a comparative analysis

Recent studies demonstrated that in addition to Na(+),K(+)-ATPase inhibition cardiotonic steroids (CTSs) affect diverse intracellular signaling pathways. This study examines the relative impact of [Na(+)](i)/[K(+)](i)-mediated and -independent signaling in transcriptomic changes triggered by the end...

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Detalles Bibliográficos
Autores principales: Klimanova, Elizaveta A., Tverskoi, Artem M., Koltsova, Svetlana V., Sidorenko, Svetlana V., Lopina, Olga D., Tremblay, Johanne, Hamet, Pavel, Kapilevich, Leonid V., Orlov, Sergei N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366943/
https://www.ncbi.nlm.nih.gov/pubmed/28345607
http://dx.doi.org/10.1038/srep45403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366943/
https://www.ncbi.nlm.nih.gov/pubmed/28345607
http://dx.doi.org/10.1038/srep45403

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