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Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na(+) and K(+): a comparative analysis

Recent studies demonstrated that in addition to Na(+),K(+)-ATPase inhibition cardiotonic steroids (CTSs) affect diverse intracellular signaling pathways. This study examines the relative impact of [Na(+)](i)/[K(+)](i)-mediated and -independent signaling in transcriptomic changes triggered by the end...

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Detalles Bibliográficos
Autores principales:	Klimanova, Elizaveta A., Tverskoi, Artem M., Koltsova, Svetlana V., Sidorenko, Svetlana V., Lopina, Olga D., Tremblay, Johanne, Hamet, Pavel, Kapilevich, Leonid V., Orlov, Sergei N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366943/ https://www.ncbi.nlm.nih.gov/pubmed/28345607 http://dx.doi.org/10.1038/srep45403

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