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Expressing anti-HIV VRC01 antibody using the murine IgG1 secretion signal in Pichia pastoris

The use of the recombinant expression platform Pichia pastoris to produce pharmaceutically important proteins has been investigated over the past 30 years. Compared to mammalian cultures, expression in P. pastoris is cheaper and faster, potentially leading to decreased costs and process development...

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Detalles Bibliográficos
Autores principales: Aw, Rochelle, McKay, Paul F., Shattock, Robin J., Polizzi, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366992/
https://www.ncbi.nlm.nih.gov/pubmed/28342171
http://dx.doi.org/10.1186/s13568-017-0372-7