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Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation

The 6-epimer of the plakortide H acid (1), along with the endoperoxides plakortide E (2), plakortin (3), and dihydroplakortin (4) have been isolated from a sample of the Caribbean sponge Plakortis halichondrioides. To perform a comparative study on the cytotoxicity towards the drug-sensitive leukemi...

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Detalles Bibliográficos
Autores principales: Schirmeister, Tanja, Oli, Swarna, Wu, Hongmei, Della Sala, Gerardo, Costantino, Valeria, Seo, Ean-Jeong, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367020/
https://www.ncbi.nlm.nih.gov/pubmed/28273803
http://dx.doi.org/10.3390/md15030063