Cargando…
Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation
The 6-epimer of the plakortide H acid (1), along with the endoperoxides plakortide E (2), plakortin (3), and dihydroplakortin (4) have been isolated from a sample of the Caribbean sponge Plakortis halichondrioides. To perform a comparative study on the cytotoxicity towards the drug-sensitive leukemi...
Autores principales: | Schirmeister, Tanja, Oli, Swarna, Wu, Hongmei, Della Sala, Gerardo, Costantino, Valeria, Seo, Ean-Jeong, Efferth, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367020/ https://www.ncbi.nlm.nih.gov/pubmed/28273803 http://dx.doi.org/10.3390/md15030063 |
Ejemplares similares
-
Polyketide Synthases in the Microbiome of the Marine Sponge Plakortis halichondrioides: A Metagenomic Update
por: Della Sala, Gerardo, et al.
Publicado: (2014) -
Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Fractionation
por: Oli, Swarna, et al.
Publicado: (2014) -
Plakofuranolactone as a Quorum Quenching Agent from the Indonesian Sponge Plakortis cf. lita
por: Costantino, Valeria, et al.
Publicado: (2017) -
Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex
por: Fattorusso, Ernesto, et al.
Publicado: (2008) -
Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts
por: Della Sala, Gerardo, et al.
Publicado: (2013)