FUSION-Guided Hypothesis Development Leads to the Identification of N(6),N(6)-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor

Chemicals found in nature have evolved over geological time scales to productively interact with biological molecules, and thus represent an effective resource for pharmaceutical development. Marine-derived bacteria are rich sources of chemically diverse, bioactive secondary metabolites, but harness...

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Detalles Bibliográficos
Autores principales: Vaden, Rachel M., Oswald, Nathaniel W., Potts, Malia B., MacMillan, John B., White, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367032/
https://www.ncbi.nlm.nih.gov/pubmed/28294973
http://dx.doi.org/10.3390/md15030075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367032/
https://www.ncbi.nlm.nih.gov/pubmed/28294973
http://dx.doi.org/10.3390/md15030075

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