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Activity of fibroblast growth factor receptor inhibitors TKI258, ponatinib and AZD4547 against TPR-FGFR1 fusion

8p11 myeloproliferative syndrome (EMS) is a rare disease characterized by the constitutive activation of fibroblast growth factor receptor 1 (FGFR1). To date, four cases of EMS with the chromosomal translocation, t(1;8)(q25;p11.2), have been reported. In the present study, TPR-FGFR1-expressing Baf3...

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Detalles Bibliográficos
Autores principales: Qiu, Xu-Hua, Li, Feng, Cao, Hong-Qin, Shao, Jing-Jing, Mei, Jian-Gang, Li, Han-Qing, Zhai, Yong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367333/
https://www.ncbi.nlm.nih.gov/pubmed/28138694
http://dx.doi.org/10.3892/mmr.2017.6140