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High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients

Extracellular vesicles (EVs) contain a wide range of RNA types with a reported prevalence of non-coding RNA. To date a comprehensive characterization of the protein coding transcripts in EVs is still lacking. We performed RNA-Sequencing (RNA-Seq) of 2 EV populations and identified a small fraction o...

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Detalles Bibliográficos
Autores principales: Conley, Andrew, Minciacchi, Valentina R., Lee, Dhong Hyun, Knudsen, Beatrice S., Karlan, Beth Y., Citrigno, Luigi, Viglietto, Giuseppe, Tewari, Muneesh, Freeman, Michael R., Demichelis, Francesca, Di Vizio, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367334/
https://www.ncbi.nlm.nih.gov/pubmed/27858503
http://dx.doi.org/10.1080/15476286.2016.1259061