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Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism

We investigated the mechanism of cancer-associated fibroblasts (CAFs) in promoting the invasion and metastasis of pancreatic cancer cells in a non-vascular manner. We verified the original generation of isolated cultured CAFs and normal fibroblasts (NFs) based on the expression of α-SMA and vimentin...

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Detalles Bibliográficos
Autores principales: Shan, Tao, Chen, Shuo, Chen, Xi, Lin, Wan Run, Li, Wei, Ma, Jiancang, Wu, Tao, Cui, Xijuan, Ji, Hong, Li, Yiming, Kang, Ya'An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367364/
https://www.ncbi.nlm.nih.gov/pubmed/28260082
http://dx.doi.org/10.3892/or.2017.5479