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EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer

cAMP signaling controls a variety of cellular functions. In addition to the well-known signal transducer cAMP-dependent protein kinase, a more recently discovered transducer is the exchange protein directly activated by cAMP (EPAC). EPAC responses are mediated by small G proteins, which regulate bio...

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Detalles Bibliográficos
Autores principales: Sun, Ding-Ping, Fang, Chia-Lang, Chen, Han-Kun, Wen, Kuo-Shan, Hseu, You-Cheng, Hung, Shih-Ting, Uen, Yih-Huei, Lin, Kai-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367365/
https://www.ncbi.nlm.nih.gov/pubmed/28260059
http://dx.doi.org/10.3892/or.2017.5442