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Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism

The structures of muscle thin filaments reconstituted using skeletal actin and cardiac troponin and tropomyosin have been determined with and without bound Ca(2+) using electron microscopy and reference-free single particle analysis. The resulting density maps have been fitted with atomic models of...

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Detalles Bibliográficos
Autores principales: Paul, Danielle M., Squire, John M., Morris, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367448/
https://www.ncbi.nlm.nih.gov/pubmed/28161413
http://dx.doi.org/10.1016/j.jsb.2017.01.004