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Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism
The structures of muscle thin filaments reconstituted using skeletal actin and cardiac troponin and tropomyosin have been determined with and without bound Ca(2+) using electron microscopy and reference-free single particle analysis. The resulting density maps have been fitted with atomic models of...
Autores principales: | Paul, Danielle M., Squire, John M., Morris, Edward P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367448/ https://www.ncbi.nlm.nih.gov/pubmed/28161413 http://dx.doi.org/10.1016/j.jsb.2017.01.004 |
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