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Therapeutic effects of proteoliposomes on X-linked chronic granulomatous disease: proof of concept using macrophages differentiated from patient-specific induced pluripotent stem cells

Chronic granulomatous disease (CGD) is a rare inherited immunodeficiency due to dysfunction of the phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex leading to severe and recurrent infections in early childhood. The main genetic form is the X-linked CGD leading to the ab...

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Detalles Bibliográficos
Autores principales: Brault, Julie, Vaganay, Guillaume, Le Roy, Aline, Lenormand, Jean-Luc, Cortes, Sandra, Stasia, Marie José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367562/
https://www.ncbi.nlm.nih.gov/pubmed/28356734
http://dx.doi.org/10.2147/IJN.S128611