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Therapeutic effects of proteoliposomes on X-linked chronic granulomatous disease: proof of concept using macrophages differentiated from patient-specific induced pluripotent stem cells
Chronic granulomatous disease (CGD) is a rare inherited immunodeficiency due to dysfunction of the phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex leading to severe and recurrent infections in early childhood. The main genetic form is the X-linked CGD leading to the ab...
Autores principales: | Brault, Julie, Vaganay, Guillaume, Le Roy, Aline, Lenormand, Jean-Luc, Cortes, Sandra, Stasia, Marie José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367562/ https://www.ncbi.nlm.nih.gov/pubmed/28356734 http://dx.doi.org/10.2147/IJN.S128611 |
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