Cargando…

Inhibition of gap junction intercellular communication is involved in silica nanoparticles-induced H9c2 cardiomyocytes apoptosis via the mitochondrial pathway

Gap junction intercellular communication (GJIC) between cardiomyocytes is essential for synchronous heart contraction and relies on connexin-containing channels. Connexin 43 (Cx43) is a major component involved in GJIC in heart tissue, and its abnormal expression is closely associated with various c...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Zhong-jun, Cui, Guan-qun, Zhang, Juan, Liu, Xiao-mei, Zhang, Zhi-hu, Jia, Qiang, Ng, Jack C, Peng, Cheng, Bo, Cun-xiang, Shao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367603/
https://www.ncbi.nlm.nih.gov/pubmed/28356735
http://dx.doi.org/10.2147/IJN.S127904