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Inhibition of gap junction intercellular communication is involved in silica nanoparticles-induced H9c2 cardiomyocytes apoptosis via the mitochondrial pathway
Gap junction intercellular communication (GJIC) between cardiomyocytes is essential for synchronous heart contraction and relies on connexin-containing channels. Connexin 43 (Cx43) is a major component involved in GJIC in heart tissue, and its abnormal expression is closely associated with various c...
Autores principales: | Du, Zhong-jun, Cui, Guan-qun, Zhang, Juan, Liu, Xiao-mei, Zhang, Zhi-hu, Jia, Qiang, Ng, Jack C, Peng, Cheng, Bo, Cun-xiang, Shao, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367603/ https://www.ncbi.nlm.nih.gov/pubmed/28356735 http://dx.doi.org/10.2147/IJN.S127904 |
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