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Breast cancer in patients with Li–Fraumeni syndrome – a case-series study and review of literature

BACKGROUND: Li–Fraumeni Syndrome (LFS) is a rare disease with autosomal dominant inheritance linked to germline mutations of tumor suppressor gene TP53. These patients are predisposed to malignancies such as sarcoma, breast cancer, leukemia, and other malignancies. Breast cancer, the most common mal...

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Detalles Bibliográficos
Autores principales: Nandikolla, Amara G, Venugopal, Sangeetha, Anampa, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367777/
https://www.ncbi.nlm.nih.gov/pubmed/28356770
http://dx.doi.org/10.2147/BCTT.S134241