Rare mutations and potentially damaging missense variants in genes encoding fibrillar collagens and proteins involved in their production are candidates for risk for preterm premature rupture of membranes

Preterm premature rupture of membranes (PPROM) is the leading identifiable cause of preterm birth with ~ 40% of preterm births being associated with PPROM and occurs in 1% - 2% of all pregnancies. We hypothesized that multiple rare variants in fetal genes involved in extracellular matrix synthesis w...

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Detalles Bibliográficos
Autores principales: Modi, Bhavi P., Teves, Maria E., Pearson, Laurel N., Parikh, Hardik I., Chaemsaithong, Piya, Sheth, Nihar U., York, Timothy P., Romero, Roberto, Strauss, Jerome F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367779/
https://www.ncbi.nlm.nih.gov/pubmed/28346524
http://dx.doi.org/10.1371/journal.pone.0174356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367779/
https://www.ncbi.nlm.nih.gov/pubmed/28346524
http://dx.doi.org/10.1371/journal.pone.0174356

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