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Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells
An increase in the osmolarity of tears induced by excessive evaporation of the aqueous tear phase is a major pathological mechanism behind dry eye. Exposure of epithelial cells on the surface of the human eye to hyperosmolarity leads to oxidative stress, mitochondrial dysfunction, and apoptosis. Eda...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367814/ https://www.ncbi.nlm.nih.gov/pubmed/28346481 http://dx.doi.org/10.1371/journal.pone.0174437 |