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Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells

An increase in the osmolarity of tears induced by excessive evaporation of the aqueous tear phase is a major pathological mechanism behind dry eye. Exposure of epithelial cells on the surface of the human eye to hyperosmolarity leads to oxidative stress, mitochondrial dysfunction, and apoptosis. Eda...

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Detalles Bibliográficos
Autores principales: Li, Yanwei, Liu, Haifeng, Zeng, Wei, Wei, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367814/
https://www.ncbi.nlm.nih.gov/pubmed/28346481
http://dx.doi.org/10.1371/journal.pone.0174437