24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation

N-methyl-D-aspartate receptors (NMDARs), a major subtype of glutamate receptor mediating excitatory transmission throughout the CNS, participate in ischemia-induced neuronal death. Unfortunately, undesired side effects have limited the strategy of inhibiting/blocking NMDARs as therapy. Targeting end...

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Detalles Bibliográficos
Autores principales: Sun, Min-Yu, Taylor, Amanda, Zorumski, Charles F., Mennerick, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367825/
https://www.ncbi.nlm.nih.gov/pubmed/28346482
http://dx.doi.org/10.1371/journal.pone.0174416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367825/
https://www.ncbi.nlm.nih.gov/pubmed/28346482
http://dx.doi.org/10.1371/journal.pone.0174416

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