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Structural, thermodynamic, and phosphatidylinositol 3‐phosphate binding properties of Phafin2

Phafin2 is a phosphatidylinositol 3‐phosphate (PtdIns(3)P) binding protein involved in the regulation of endosomal cargo trafficking and lysosomal induction of autophagy. Binding of Phafin2 to PtdIns(3)P is mediated by both its PH and FYVE domains. However, there are no studies on the structural bas...

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Detalles Bibliográficos
Autores principales: Tang, Tuo‐Xian, Jo, Ami, Deng, Jingren, Ellena, Jeffrey F., Lazar, Iulia M., Davis, Richey M., Capelluto, Daniel G. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368057/
https://www.ncbi.nlm.nih.gov/pubmed/28152563
http://dx.doi.org/10.1002/pro.3128