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An approach to functionally relevant clustering of the protein universe: Active site profile‐based clustering of protein structures and sequences

Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification—amino acids that distinguish details between functional families within a superfamily. Active site profiling was developed to ident...

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Detalles Bibliográficos
Autores principales: Knutson, Stacy T., Westwood, Brian M., Leuthaeuser, Janelle B., Turner, Brandon E., Nguyendac, Don, Shea, Gabrielle, Kumar, Kiran, Hayden, Julia D., Harper, Angela F., Brown, Shoshana D., Morris, John H., Ferrin, Thomas E., Babbitt, Patricia C., Fetrow, Jacquelyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368075/
https://www.ncbi.nlm.nih.gov/pubmed/28054422
http://dx.doi.org/10.1002/pro.3112