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An approach to functionally relevant clustering of the protein universe: Active site profile‐based clustering of protein structures and sequences
Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification—amino acids that distinguish details between functional families within a superfamily. Active site profiling was developed to ident...
Autores principales: | Knutson, Stacy T., Westwood, Brian M., Leuthaeuser, Janelle B., Turner, Brandon E., Nguyendac, Don, Shea, Gabrielle, Kumar, Kiran, Hayden, Julia D., Harper, Angela F., Brown, Shoshana D., Morris, John H., Ferrin, Thomas E., Babbitt, Patricia C., Fetrow, Jacquelyn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368075/ https://www.ncbi.nlm.nih.gov/pubmed/28054422 http://dx.doi.org/10.1002/pro.3112 |
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