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Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy

Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate a special transcriptional program that renders them more aggressive biological behaviors. Hypoxia-inducible fac...

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Detalles Bibliográficos
Autores principales: Yu, Tianchi, Tang, Bo, Sun, Xueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368132/
https://www.ncbi.nlm.nih.gov/pubmed/28332352
http://dx.doi.org/10.3349/ymj.2017.58.3.489