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Potential Antitumor Activity of SIM-89 in Non-Small Cell Lung Cancer Cells

PURPOSE: c-Met and its ligand, hepatocyte growth factor (HGF), play a critical role in oncogenesis and metastatic progression. The aim of this study was to identify inhibited enzymogram and to test the antitumor activity of SIM-89 (a c-Met receptor tyrosine kinase inhibitor) in non-small cell lung c...

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Detalles Bibliográficos
Autores principales: Pei, Jun, Chu, Tianqing, Shao, Minhua, Teng, Jiajun, Sha, Huifang, Gu, Aiqing, Li, Rong, Qian, Jialin, Mao, Weifeng, Li, Ying, Han, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368144/
https://www.ncbi.nlm.nih.gov/pubmed/28332364
http://dx.doi.org/10.3349/ymj.2017.58.3.581