Insights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine Residue

UV radiation triggers the formation of 5-thyminyl-5,6-dihydrothymine, i.e., the spore photoproduct (SP), in the genomic DNA of bacterial endospores. These SPs, if not repaired in time, may lead to genome instability and cell death. SP is mainly repaired by spore photoproduct lyase (SPL) during spore...

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Detalles Bibliográficos
Autores principales: Yang, Linlin, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368176/
https://www.ncbi.nlm.nih.gov/pubmed/28401144
http://dx.doi.org/10.3389/fchem.2017.00014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368176/
https://www.ncbi.nlm.nih.gov/pubmed/28401144
http://dx.doi.org/10.3389/fchem.2017.00014

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