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Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function

The active zone (AZ) matrix of presynaptic terminals coordinates the recruitment of voltage-gated calcium channels (VGCCs) and synaptic vesicles to orchestrate neurotransmitter release. However, the spatial organization of the AZ and how it controls vesicle fusion remain poorly understood. Here, we...

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Detalles Bibliográficos
Autores principales: Glebov, Oleg O., Jackson, Rachel E., Winterflood, Christian M., Owen, Dylan M., Barker, Ellen A., Doherty, Patrick, Ewers, Helge, Burrone, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368346/
https://www.ncbi.nlm.nih.gov/pubmed/28297674
http://dx.doi.org/10.1016/j.celrep.2017.02.064