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Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function
The active zone (AZ) matrix of presynaptic terminals coordinates the recruitment of voltage-gated calcium channels (VGCCs) and synaptic vesicles to orchestrate neurotransmitter release. However, the spatial organization of the AZ and how it controls vesicle fusion remain poorly understood. Here, we...
Autores principales: | Glebov, Oleg O., Jackson, Rachel E., Winterflood, Christian M., Owen, Dylan M., Barker, Ellen A., Doherty, Patrick, Ewers, Helge, Burrone, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368346/ https://www.ncbi.nlm.nih.gov/pubmed/28297674 http://dx.doi.org/10.1016/j.celrep.2017.02.064 |
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