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Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms

Age-associated neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and the polyglutamine (polyQ) diseases, are becoming prevalent as a consequence of elongation of the human lifespan. Although various rodent models have been developed to study and overcome these diseases, t...

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Detalles Bibliográficos
Autores principales: Tomioka, Ikuo, Ishibashi, Hidetoshi, Minakawa, Eiko N., Motohashi, Hideyuki H., Takayama, Osamu, Saito, Yuko, Popiel, H. Akiko, Puentes, Sandra, Owari, Kensuke, Nakatani, Terumi, Nogami, Naotake, Yamamoto, Kazuhiro, Noguchi, Satoru, Yonekawa, Takahiro, Tanaka, Yoko, Fujita, Naoko, Suzuki, Hikaru, Kikuchi, Hisae, Aizawa, Shu, Nagano, Seiichi, Yamada, Daisuke, Nishino, Ichizo, Ichinohe, Noritaka, Wada, Keiji, Kohsaka, Shinichi, Nagai, Yoshitaka, Seki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368386/
https://www.ncbi.nlm.nih.gov/pubmed/28374014
http://dx.doi.org/10.1523/ENEURO.0250-16.2017