Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways

Enteric glial cells (EGCs) are components of the intestinal epithelial barrier essential for regulating the enteric nervous system. Clostridium difficile is the most common cause of antibiotic-associated colitis, toxin B (TcdB) being the major virulence factor, due to its ability to breach the intes...

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Detalles Bibliográficos
Autores principales: Macchioni, Lara, Davidescu, Magdalena, Fettucciari, Katia, Petricciuolo, Maya, Gatticchi, Leonardo, Gioè, Davide, Villanacci, Vincenzo, Bellini, Massimo, Marconi, Pierfrancesco, Roberti, Rita, Bassotti, Gabrio, Corazzi, Lanfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368562/
https://www.ncbi.nlm.nih.gov/pubmed/28349972
http://dx.doi.org/10.1038/srep45569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368562/
https://www.ncbi.nlm.nih.gov/pubmed/28349972
http://dx.doi.org/10.1038/srep45569

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