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Targeting Splicing in the Treatment of Human Disease

The tightly regulated process of precursor messenger RNA (pre-mRNA) alternative splicing (AS) is a key mechanism in the regulation of gene expression. Defects in this regulatory process affect cellular functions and are the cause of many human diseases. Recent advances in our understanding of splici...

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Detalles Bibliográficos
Autores principales: Suñé-Pou, Marc, Prieto-Sánchez, Silvia, Boyero-Corral, Sofía, Moreno-Castro, Cristina, El Yousfi, Younes, Suñé-Negre, Josep Mª, Hernández-Munain, Cristina, Suñé, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368691/
https://www.ncbi.nlm.nih.gov/pubmed/28245575
http://dx.doi.org/10.3390/genes8030087