Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD)

FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent hereditary myopathies and is generally characterized by progressive muscle atrophy affecting the face, scapular fixators; upper arms and distal lower legs. The FSHD locus maps to a macrosatellite D4Z4 repeat array on chromoso...

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Detalles Bibliográficos
Autores principales: Ansseau, Eugénie, Vanderplanck, Céline, Wauters, Armelle, Harper, Scott Q., Coppée, Frédérique, Belayew, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368697/
https://www.ncbi.nlm.nih.gov/pubmed/28273791
http://dx.doi.org/10.3390/genes8030093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368697/
https://www.ncbi.nlm.nih.gov/pubmed/28273791
http://dx.doi.org/10.3390/genes8030093

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