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Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD)
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent hereditary myopathies and is generally characterized by progressive muscle atrophy affecting the face, scapular fixators; upper arms and distal lower legs. The FSHD locus maps to a macrosatellite D4Z4 repeat array on chromoso...
Autores principales: | Ansseau, Eugénie, Vanderplanck, Céline, Wauters, Armelle, Harper, Scott Q., Coppée, Frédérique, Belayew, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368697/ https://www.ncbi.nlm.nih.gov/pubmed/28273791 http://dx.doi.org/10.3390/genes8030093 |
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