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Regulation of DNA Replication through Natural Impediments in the Eukaryotic Genome
All living organisms need to duplicate their genetic information while protecting it from unwanted mutations, which can lead to genetic disorders and cancer development. Inaccuracies during DNA replication are the major cause of genomic instability, as replication forks are prone to stalling and col...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368702/ https://www.ncbi.nlm.nih.gov/pubmed/28272375 http://dx.doi.org/10.3390/genes8030098 |