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Regulation of DNA Replication through Natural Impediments in the Eukaryotic Genome

All living organisms need to duplicate their genetic information while protecting it from unwanted mutations, which can lead to genetic disorders and cancer development. Inaccuracies during DNA replication are the major cause of genomic instability, as replication forks are prone to stalling and col...

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Detalles Bibliográficos
Autores principales: Gadaleta, Mariana C., Noguchi, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368702/
https://www.ncbi.nlm.nih.gov/pubmed/28272375
http://dx.doi.org/10.3390/genes8030098