The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences

Paired box 4 (PAX4) is a key factor in the generation of insulin producing β-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of β-cells that are prone to proliferation and more resistant to stress-induced apoptosis. The importance of this transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorenzo, Petra I., Juárez-Vicente, Francisco, Cobo-Vuilleumier, Nadia, García-Domínguez, Mario, Gauthier, Benoit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368705/
https://www.ncbi.nlm.nih.gov/pubmed/28282933
http://dx.doi.org/10.3390/genes8030101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368705/
https://www.ncbi.nlm.nih.gov/pubmed/28282933
http://dx.doi.org/10.3390/genes8030101

Ejemplares similares