Cargando…
The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences
Paired box 4 (PAX4) is a key factor in the generation of insulin producing β-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of β-cells that are prone to proliferation and more resistant to stress-induced apoptosis. The importance of this transcription...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368705/ https://www.ncbi.nlm.nih.gov/pubmed/28282933 http://dx.doi.org/10.3390/genes8030101 |