Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

BACKGROUND: Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models. METHODS: Safety, tolerability, and plasma pharmacokinetics of singl...

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Detalles Bibliográficos
Autores principales: Chandorkar, Gurudatt, Zhan, Qiao, Donovan, Julie, Rege, Shruta, Patino, Hernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368910/
https://www.ncbi.nlm.nih.gov/pubmed/28347318
http://dx.doi.org/10.1186/s40360-017-0123-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368910/
https://www.ncbi.nlm.nih.gov/pubmed/28347318
http://dx.doi.org/10.1186/s40360-017-0123-z

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