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Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS)

BACKGROUND: Nocturia (the symptom of needing to wake up to pass urine) is common in progressive Multiple Sclerosis (MS) patients. Moderate-to-severe nocturia affects quality of life, can exacerbate fatigue and may affect capacity to carry out daily activities. Melatonin is a natural hormone regulati...

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Detalles Bibliográficos
Autores principales: Delgado, D., Canham, L., Cotterill, N., Cottrell, D., Drake, M. J., Inglis, K., Owen, D., White, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368919/
https://www.ncbi.nlm.nih.gov/pubmed/28347292
http://dx.doi.org/10.1186/s12883-017-0845-y