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Uricosuric targets of tranilast

Uric acid, generated from the metabolism of purines, has both proven and emerging roles in human disease. Serum uric acid in humans is determined by production and by the net balance of reabsorption and secretion in kidney and intestine. In the human kidney, epithelial reabsorption dominates over se...

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Detalles Bibliográficos
Autores principales: Mandal, Asim K., Mercado, Adriana, Foster, Andria, Zandi‐Nejad, Kambiz, Mount, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368959/
https://www.ncbi.nlm.nih.gov/pubmed/28357121
http://dx.doi.org/10.1002/prp2.291