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In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation

Individual differences in drug metabolism contribute to interindividual variation that characterizes responses to drugs and risk in exposure to foreign chemicals. Large individual differences are found in expression levels of CYP1A2, a major drug‐metabolizing enzyme. Underlying causes for this varia...

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Detalles Bibliográficos
Autores principales: Xie, ChengHui, Pogribna, Marta, Word, Beverly, Lyn‐Cook, Lascelles, Lyn‐Cook, Beverly D., Hammons, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368963/
https://www.ncbi.nlm.nih.gov/pubmed/28357125
http://dx.doi.org/10.1002/prp2.299