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In vitro analysis of factors influencing CYP1A2 expression as potential determinants of interindividual variation
Individual differences in drug metabolism contribute to interindividual variation that characterizes responses to drugs and risk in exposure to foreign chemicals. Large individual differences are found in expression levels of CYP1A2, a major drug‐metabolizing enzyme. Underlying causes for this varia...
Autores principales: | Xie, ChengHui, Pogribna, Marta, Word, Beverly, Lyn‐Cook, Lascelles, Lyn‐Cook, Beverly D., Hammons, George J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368963/ https://www.ncbi.nlm.nih.gov/pubmed/28357125 http://dx.doi.org/10.1002/prp2.299 |
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