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TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H(2)O(2)

BACKGROUND: The fate of hydrogen peroxide (H(2)O(2)) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thiol oxidases and peroxiredoxins, in vitro, and the consequences of their genetic manipulation, in vivo. Over the years hints have suggested that glu...

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Detalles Bibliográficos
Autores principales: Melo, Eduardo Pinho, Lopes, Carlos, Gollwitzer, Peter, Lortz, Stephan, Lenzen, Sigurd, Mehmeti, Ilir, Kaminski, Clemens F., Ron, David, Avezov, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368998/
https://www.ncbi.nlm.nih.gov/pubmed/28347335
http://dx.doi.org/10.1186/s12915-017-0367-5