Cargando…

TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H(2)O(2)

BACKGROUND: The fate of hydrogen peroxide (H(2)O(2)) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thiol oxidases and peroxiredoxins, in vitro, and the consequences of their genetic manipulation, in vivo. Over the years hints have suggested that glu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Melo, Eduardo Pinho, Lopes, Carlos, Gollwitzer, Peter, Lortz, Stephan, Lenzen, Sigurd, Mehmeti, Ilir, Kaminski, Clemens F., Ron, David, Avezov, Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368998/ https://www.ncbi.nlm.nih.gov/pubmed/28347335 http://dx.doi.org/10.1186/s12915-017-0367-5

Ejemplares similares

ERO1-independent production of H(2)O(2) within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
por: Konno, Tasuku, et al.
Publicado: (2015)

Single particle trajectories reveal active Endoplasmic Reticulum luminal flow
por: Holcman, David, et al.
Publicado: (2018)

Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species
por: Rebiger, Lars, et al.
Publicado: (2016)

Intracellular Sources of ROS/H(2)O(2) in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum
por: Konno, Tasuku, et al.
Publicado: (2021)

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
por: Avezov, Edward, et al.
Publicado: (2015)

The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes
por: Lu, Meng, et al.
Publicado: (2020)

Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis
por: Nakamura, Kimitoshi, et al.
Publicado: (2000)

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants
por: Tsunoda, Satoshi, et al.
Publicado: (2014)

CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy
por: Ishii, Shunsuke, et al.
Publicado: (2023)

Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP
por: Melo, Eduardo Pinho, et al.
Publicado: (2022)

Depletion of Luminal Pyridine Nucleotides in the Endoplasmic Reticulum Activates Autophagy with the Involvement of mTOR Pathway
por: Kapuy, Orsolya, et al.
Publicado: (2013)

Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
por: Carrara, Marta, et al.
Publicado: (2015)

Endoplasmic Reticulum Remodeling Tunes IP(3)-Dependent Ca(2+) Release Sensitivity
por: Sun, Lu, et al.
Publicado: (2011)

Head-to-tail oligomerization of calsequestrin: a novel mechanism for heterogeneous distribution of endoplasmic reticulum luminal proteins
por: Gatti, Giuliana, et al.
Publicado: (2001)

Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity
por: Chernorudskiy, Alexander, et al.
Publicado: (2020)

Calumenin-1 Interacts with Climp63 to Cooperatively Determine the Luminal Width and Distribution of Endoplasmic Reticulum Sheets
por: Shen, Birong, et al.
Publicado: (2019)

A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans
por: Miedel, Mark T., et al.
Publicado: (2012)

Endoplasmic reticulum oxidoreductin provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics
por: Ugalde, José Manuel, et al.
Publicado: (2022)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

Disturbed phospholipid homeostasis in endoplasmic reticulum initiates tri-o-cresyl phosphate-induced delayed neurotoxicity
por: Zhu, Li, et al.
Publicado: (2016)

The fine-tuning of endoplasmic reticulum stress response and autophagy activation during trophoblast syncytialization
por: Bastida-Ruiz, Daniel, et al.
Publicado: (2019)

Z-α(1)-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state
por: Chambers, Joseph E., et al.
Publicado: (2022)

Subdomain-Specific Localization of Climp-63 (P63) in the Endoplasmic Reticulum Is Mediated by Its Luminal α-Helical Segment
por: Klopfenstein, Dieter R., et al.
Publicado: (2001)

To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2
por: Kuśnierczyk, Piotr
Publicado: (2022)

Construction of the endoplasmic reticulum
Publicado: (1989)

Cholesterol metabolism—physiological regulation and pathophysiological deregulation by the endoplasmic reticulum
por: Röhrl, Clemens, et al.
Publicado: (2018)

Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins – mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor
por: Albert, Katrina, et al.
Publicado: (2019)

Is all of the endoplasmic reticulum created equal? The effects of the heterogeneous distribution of endoplasmic reticulum Ca(2+)-handling proteins
por: Papp, S., et al.
Publicado: (2003)

Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress
por: Song, Yong Bhum, et al.
Publicado: (2022)

Control of cardiac ryanodine receptor by sarcoplasmic reticulum luminal Ca(2+)
por: Jones, Peter P., et al.
Publicado: (2017)

Endoplasmic Reticulum Stress and Cancer
por: Yadav, Raj Kumar, et al.
Publicado: (2014)

Regulation of endoplasmic reticulum functions
por: Namba, Takushi
Publicado: (2015)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Autophagic degradation of the endoplasmic reticulum
por: NAKATOGAWA, Hitoshi
Publicado: (2020)

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox
por: Avezov, Edward, et al.
Publicado: (2013)

Chronic inhibition of endoplasmic reticulum calcium-release channels and calcium-ATPase lengthens the period of hepatic clock gene Per1
por: Báez-Ruiz, Adrián, et al.
Publicado: (2011)

Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model
por: Lay, Angelina J., et al.
Publicado: (2022)

Maintenance of Calcium Homeostasis in the Endoplasmic Reticulum by Bcl-2
por: He, Huiling, et al.
Publicado: (1997)

Role of PKD2 in the endoplasmic reticulum calcium homeostasis
por: Liu, Xiong, et al.
Publicado: (2022)

CRELD2, endoplasmic reticulum stress, and human diseases
por: Tang, Qin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sf1q99oc3k72okl2t2dj0hdpoa