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A Cell-Based Assay to Assess Hemichannel Function

Activation of connexin hemichannels is involved in the pathophysiology of disorders that include deafness, stroke, and cardiac infarct. This aspect makes hemichannels an attractive therapeutic target. Unfortunately, most available inhibitors are not selective or isoform specific, which hampers their...

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Detalles Bibliográficos
Autores principales: Krishnan, Srinivasan, Fiori, Mariana C., Cuello, Luis G., Altenberg, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369048/
https://www.ncbi.nlm.nih.gov/pubmed/28356896