Cargando…

Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism

Mitochondrial ATP-Mg/Pi carriers import adenine nucleotides into the mitochondrial matrix and export phosphate to the cytosol. They are calcium-regulated to control the size of the matrix adenine nucleotide pool in response to cellular energetic demands. They consist of three domains: an N-terminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Harborne, Steven P. D., King, Martin S., Crichton, Paul G., Kunji, Edmund R. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369052/
https://www.ncbi.nlm.nih.gov/pubmed/28350015
http://dx.doi.org/10.1038/srep45383