Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88

BACKGROUND: GPR88 is an orphan G protein-coupled receptor highly expressed in the striatum and is implicated in basal ganglia-associated disorders. However, the receptor functions of GPR88 are still largely unknown due to the lack of potent and selective ligands appropriate for central nervous syste...

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Detalles Bibliográficos
Autores principales: Decker, Ann M., Gay, Elaine A., Mathews, Kelly M., Rosa, Taylor C., Langston, Tiffany L., Maitra, Rangan, Jin, Chunyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369193/
https://www.ncbi.nlm.nih.gov/pubmed/28347302
http://dx.doi.org/10.1186/s12929-017-0330-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369193/
https://www.ncbi.nlm.nih.gov/pubmed/28347302
http://dx.doi.org/10.1186/s12929-017-0330-3

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